Antibacterial Activity and Cytocompatibility of Bone Cement Enriched with Antibiotic, Nanosilver, and Nanocopper for Bone Regeneration
نویسندگان
چکیده
منابع مشابه
Antibacterial activity of bone cement containing quaternary ammonium polyethyleneimine nanoparticles.
Sir, A bone cement mantle is commonly used in orthopaedic surgery, and creates an ideal environment for bacterial growth. Bacterial infection following joint replacement surgery is a catastrophic complication. It is estimated that infections occur in up to about 2% of primary hip and knee replacements, whereas revision surgery carries a 2–3-fold higher risk. The most common bacteria isolated fr...
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Abstract Objective: The aim of this study was to evaluate the efficacy of antibiotic-loaded bone cement in controlling local infection and in regard to its physical characteristics, elastic modulus, and tensile strength in-vitro. Methods: Acrylic bone cement, based on polymethylmethacrylate (PMMA) was mixed with the powder form of three antibiotics, i.e., gentamicin, tobramycin, and...
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Various biological bone g rafts have been used for osteogenes i s , osteoconduction and even osteoinduction, but due to systemic influences and local factors, the outcome of successful incorporation of a bone graft has not been satisfactory. This study was therefore conducted on 15 clinically healthy adult dogs between 1 to 3 years of age weighing 20 to 30 kg to evaluate the effect of bo...
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References 1 Nordmann P, Cuzon G, Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 2009; 9: 228–36. 2 Wolter DJ, Kurpiel PM, Woodford N et al. Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4. Antimicrob Agents Chemother 2009; 53: 557–62. 3 Endimiani A, Patel G, Hujer K...
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Implant-associated infections, which are normally induced by microbial adhesion and subsequent biofilm formation, are a major cause of morbidity and mortality. Therefore, practical approaches to prevent implant-associated infections are in great demand. Inspired by adhesive proteins in mussels, here we have developed a novel antibiotic-decorated titanium (Ti) material with enhanced antibacteria...
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ژورنال
عنوان ژورنال: Nanomaterials
سال: 2019
ISSN: 2079-4991
DOI: 10.3390/nano9081114